Diker et al found AF in 29% of patients with isolated mitral stenosis, in 16% with isolated mitral regurgitation, in 52% in combined mitral stenosis and regurgitation, but in only 1% of patients with aortic valvular disease. The incidence of AF differs according to the type and the severity of valvular affection. In areas with a high prevalence of rheumatic heart disease, AF is common, especially in young females of child-bearing age. Compared to women without AF, foetal birth weights were similar, but the rate of admission to the neonatal intensive care unit for neonates was higher (10.8 vs. Among AF patients, adverse maternal cardiac events were rare. The odds of AF episodes were higher during the third trimester compared to the first trimester (odds ratio 3.2, 95% confidence interval : 1.5-7.7). Older age was associated with higher odds of having AF. The prevalence of AF (per 100,000 women) in white, black, Asian, and Hispanic women was 111.6, 101.7, 45.0, and 34.3, respectively. In a population-based study performed in California, USA, between 20, there were 264,730 qualifying pregnancies among which AF was noted in 157 pregnancies (129 women 61.3 per 100,000 women, or 59.3 per 100,000 pregnancies). AF in Western countriesĪF is unusual during pregnancy in Western countries and, if it occurs, it is either a benign, lone AF or a haemodynamically significant AF, with or without structural heart disease. According to the 2018 European guidelines, the incidence of AF during pregnancy is 27/100,000. IncidenceĪF is the most common arrhythmia in adults, affecting nearly 0.5-1% of the total population and >8% of patients older than 80 years. Whilst it is a concern that this hypercoagulable state can predispose pregnant women with AF to an elevated risk of thromboembolic complications, the extent of this risk is not known. Pregnancy is accompanied by an increased concentration of clotting factors and a decrease in anticoagulant factors, resulting in a hypercoagulable state. The occurrence of rapid AF during pregnancy intensifies the haemodynamic burden over the heart and leads to heart failure. Normal pregnancy is associated with increased plasma volume, increased heart rate and increased cardiac output. Haemodynamic abnormalities and thromboembolic events related to AF result in significant morbidity and mortality. Atrial fibrillation (AF) is one of the most common cardiac arrhythmias.
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